Holisal Dental Gel 15g

Holisal Dental Gel 15 g

Holisal Dental Gel 15 g Composition
1 g contains:

Active ingredients: choline salicylate – 87.1 mg, cetyl alcohol – 0.1 mg.

Excipients: hytellose – 20.0 mg, methyl parahydroxybenzoate – 1.5 mg, propyl parahydroxybenzoate – 0.8 mg, glycerol – 50.0 mg, anise seed oil – 1.61 mg, ethanol 96% – 390.0 mg, water – up to 1000 mg.

Description

A transparent, colorless, homogeneous mass with an anise oil odor. Holisal is sugar-free.

Pharmacological action

When applied topically, the main active ingredient, choline salicylate, is rapidly absorbed through the oral mucosa, providing local analgesic, anti-inflammatory, and antipyretic effects. It inhibits cyclooxygenase activity, macrophage and neutrophil function, and interleukin-1 production, as well as prostaglandin synthesis. It also has antimicrobial and antifungal effects (in acidic and alkaline environments). Cetyl chloride is an antiseptic, effective against bacteria, fungi, and also viruses. The ethanol-containing gel adhesive base ensures rapid onset of action and maintains the active ingredients on the mucous membrane for a long time. The analgesic effect begins within 2-3 minutes, with a duration of 2-8 hours.

Pharmacokinetics

It is well absorbed when applied to mucous membranes.

Holisal Indications

For topical application to the oral mucosa as an analgesic and anti-inflammatory agent in the treatment of periodontal disease, oral mucosal lesions, and conditions associated with inflammation and pain, including:

stomatitis of various etiologies,
gingivitis,
periodontitis,
oral mucosal lesions caused by wearing dentures,
oral mucosal trauma,
teething pain in children,
cheilitis,
oral mucosal candidiasis,
minor oral surgeries,
lichen planus localized to the oral mucosa,
oral mucosal lesions associated with Stevens-Johnson syndrome as part of combination therapy.

Dosage and Administration

Topically. Holisal is administered 2-3 times daily before meals (for pain relief) or after meals and before bedtime. A 1 cm strip of gel for adults and a 0.5 cm strip for children is squeezed onto a clean finger and rubbed into the affected area of ​​the oral mucosa with gentle massaging movements.

For periodontal disease, the gel is injected into pockets, applied as a compress, and also gently rubbed into the gums 1-2 times daily.

Holisal contraindications

Hypersensitivity to salicylates and other components of the drug.

Holisal Side effects

Short-term mild burning sensation at the application site, which resolves spontaneously.  Allergic reactions.

Interactions

When you use Holisal, the effects of other anti-inflammatory, antipyretic, and pain medications may increase.

Dosage Form

Dental Gel

10 g or 15 g aluminum tubes with a membrane and a polymer cap (with a stitch).

Storage Instructions

At a temperature not exceeding 25°C. Do not freeze.
Keep out of reach of children.

Shelf Life

3 years.
Do not use after the expiration date printed on the packaging.

Manufacturer

Pharmaceutical plant Yelfa A.O.,

58-500 Elena Gura, 21 V. Polya str., Poland

Holisal Dental Gel 15g  feedbacks

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