Acyclovir Eye Ointment 3%
Acyclovir Eye Ointment 3% 5g
Composition of Acyclovir Eye Ointment: 1 g of ophthalmic ointment contains: active ingredient: acyclovir 30 mg; excipient: petrolatum.
Pharmacological action
Acyclovir is an antiviral ophthalmic drug. It exhibits activity against the Varicella-Zoster family of viruses, as well as Herpes simplex types 1 and 2. Acyclovir triphosphate acts as a nonspecific inhibitor, preventing viral DNA synthesis without damaging host cells. Acyclovir ophthalmic ointment is rapidly absorbed by corneal epithelial cells and periorbital tissues, creating the concentration of the drug in the aqueous humor necessary to suppress the virus.
Indications f Acyclovir Eye Ointment
Herpetic keratitis caused by the herpes simplex virus types 1 or 2.
Contraindications
— Breastfeeding; — Hypersensitivity to acyclovir or valacyclovir.
Side effects
Side effects of the drug include: common: mild burning; uncommon: punctate superficial keratopathy, conjunctivitis; and in isolated cases, blepharitis. Allergic reactions are also possible: very rare: hypersensitivity reactions, including angioedema.
How to use, course of administration, and dosage f Acyclovir Eye Ointment
For adults and children, apply a 1 cm strip of ophthalmic ointment to the lower conjunctival sac 5 times daily (every 4 hours) until healing. Continue treatment for another 3 days after healing.
Interactions
Using acyclovir with immunostimulants enhances the effect of acyclovir.
Special instructions
The earlier treatment is started (at the first signs of infection), the higher the effectiveness of treatment. Contact lenses are not recommended during treatment with acyclovir ophthalmic ointment. The immune system is important for the therapeutic effect of acyclovir. Patients with weakened immune systems who are receiving topical acyclovir ointment should receive systemic administration, as is the case with severe and recurrent herpes infections. Effects on the ability to drive and operate machinery: After using the ointment, a temporary decrease in visual acuity is possible. Driving and engaging in activities requiring increased alertness and reaction time are not recommended until visual acuity is restored.
Dosage Form
Acyclovir eye ointment. Ointment for topical use
Storage Instructions
Store in a dry, dark place, out of the reach of children, at a temperature not exceeding 15°C.
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