Exenza Zolmitriptan Nasal Spray

Exenza Zolmitriptan nasal spray 2.5 mg/dose bottle of 20 doses

The active ingredient of  Exenza Nasal Spray is zolmitriptan 2.5 mg.
Excipients: anhydrous citric acid, dexpanthenol, benzalkonium chloride, disodium hydrogen phosphate dihydrate, purified water.

Indications for Use Exenza Zolmitriptan nasal spray

Treatment (relief) of migraines with or without aura in adults, as well as for the treatment (relief) of acute cluster headaches in adults.

The drug reduces the degree of vasodilation. This, in turn, leads to headache relief and other attack symptoms, such as:

feeling unwell (nausea or vomiting) and increased sensitivity to light and sounds during a migraine attack,
lacrimation and redness of the eye (conjunctival injection), as well as discharge and nasal congestion on the side of the headache during a cluster headache attack.
The drug is effective only after a migraine or cluster headache attack has already begun.

Directions for Use Exenza Zolmitriptan nasal spray

Always use this medication exactly as directed by your doctor or pharmacist. If in doubt, consult your doctor or pharmacist.
Exenza is not indicated for the prevention of migraine or cluster headaches.

Migraine Treatment

The recommended dose for treating a migraine attack is 2.5 mg or 5 mg. For patients who do not achieve a satisfactory response with 2.5 mg, a 5 mg dose may be effective for subsequent attacks.
It is preferable to take Exenza as soon as possible after the onset of a migraine headache, but the drug is also effective when taken later.

Cluster Headache Treatment

The recommended dose for treating a cluster headache attack is 5 mg or 10 mg. For patients who do not achieve a satisfactory response with 5 mg, a 10 mg dose may be effective for subsequent attacks.
The total daily dose should not exceed 10 mg, therefore, no more than 4 doses of zolmitriptan 2.5 mg or 2 doses of zolmitriptan 5 mg should be taken in any 24-hour period.

Administration

Intranasally (by spraying into the nose).
Before using Exenza, clear your nostrils (gently blow your nose).
Before using Exenza for the first time, press the sprayer several times, directing the spray into the air until a uniform mist forms.
If more than four weeks have passed since the last use, the first spray should be directed into the air to prevent underdosing. Store the bottle with the cap tightly closed between uses.
When using, hold the bottle with the sprayer facing upward. Tilt your head slightly forward, insert the sprayer into one nostril, tilting the tip of the sprayer slightly away from the center of the nose, and press once. Repeat with the other nostril if necessary.

Single or multiple sprays can be administered in either nostril.

Contraindications

Do not use Exenza:

– if you are allergic to zolmitriptan or any other ingredients of this medication;

-Age over 65 years;

– if you have uncontrolled high blood pressure;

– heart problems such as heart attack, coronary artery disease, or angina, coronary artery spasm/Prinzmetal’s angina, shortness of breath, or chest tightness;

– if you have peripheral arterial disease;

– if you have had a stroke or other short-term stroke-like symptoms (transient ischemic attack);

– you have severe kidney disease (renal failure);

– if you are already taking other medications to treat migraines (e.g., ergotamine or its derivatives (including methysergide)), or other triptans (e.g., sumatriptan or naratriptan), or medications to treat depression (monoamine oxidase inhibitors). For more detailed information, see the section “Other medications and

Storage conditions

below 30 °C.

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